The excess numbers of peritoneal macrophages in granulocyte-macrophage colony-stimulating factor transgenic mice are generated by local proliferation

Mice transgenic for the hemopoietic growth factor, granulocyte- macrophage colony-stimulating factor (GM-CSF), exhibit a sustained elevation of GM-CSF levels and a 50-100-fold elevation of peritoneal macrophage cell numbers. The excess cell numbers were found to be generated in pre-adult life, with...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1992
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119164/