The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells

Activation via the T lymphocyte cell surface molecule CD28 provides a potent amplification signal for interleukin 2 (IL-2) production in several in vitro systems. The B lymphocyte activation antigen, B7/BB1, is a natural ligand for CD28. Here we investigate the role of CD28 and B7/BB1 in primary act...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1991
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118811/