Histologic transformation of follicular lymphoma to diffuse lymphoma represents tumor progression by a single malignant B cell
To investigate the clonal relationship between follicular lymphoma (FL) and transformed diffuse lymphoma (tDL), we examined the expression of tumor idiotype, immunoglobulin (Ig) gene rearrangements and sequence of Ig variable genes in paired tissue specimens. All 16 cases analyzed expressed surface...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1991
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118744/ |