Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination

V(D)J recombination and immunoglobulin class switch recombination (CSR) are two somatic rearrangement mechanisms that proceed through the introduction of double-strand breaks (DSBs) in DNA. Although the DNA repair factor XRCC4 is essential for the resolution of DNA DSB during V(D)J recombination, it...

Full description

Bibliographic Details
Main Authors: Soulas-Sprauel, Pauline, Le Guyader, Gwenaël, Rivera-Munoz, Paola, Abramowski, Vincent, Olivier-Martin, Christelle, Goujet-Zalc, Cécile, Charneau, Pierre, de Villartay, Jean-Pierre
Format: Online
Language:English
Published: The Rockefeller University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118634/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118634/

Similar Items