Thromboxane A2 is a key regulator of pathogenesis during Trypanosoma cruzi infection

Chagas' disease is caused by infection with the parasite Trypanosoma cruzi. We report that infected, but not uninfected, human endothelial cells (ECs) released thromboxane A2 (TXA2). Physical chromatography and liquid chromatography-tandem mass spectrometry revealed that TXA2 is the predominant...

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Bibliographic Details
Main Authors: Ashton, Anthony W., Mukherjee, Shankar, Nagajyothi, FNU, Huang, Huan, Braunstein, Vicki L., Desruisseaux, Mahalia S., Factor, Stephen M., Lopez, Lillie, Berman, Joan W., Wittner, Murray, Scherer, Philipp E., Capra, Valerie, Coffman, Thomas M., Serhan, Charles N., Gotlinger, Katherine, Wu, Kenneth K., Weiss, Louis M., Tanowitz, Herbert B.
Format: Online
Language:English
Published: The Rockefeller University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118547/