Molecular mechanism of mast cell–mediated innate defense against endothelin and snake venom sarafotoxin
Mast cells are protective against snake venom sarafotoxins that belong to the endothelin (ET) peptide family. The molecular mechanism underlying this recently recognized innate defense pathway is unknown, but secretory granule proteases have been invoked. To specifically disrupt a single protease fu...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118486/ |