NF-κB translocation prevents host cell death after low-dose challenge by Legionella pneumophila

Legionella pneumophila, the causative agent of Legionnaires' disease, grows within macrophages and manipulates target cell signaling. Formation of a Legionella-containing replication vacuole requires the function of the bacterial type IV secretion system (Dot/Icm), which transfers protein subs...

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Bibliographic Details
Main Authors: Losick, Vicki P., Isberg, Ralph R.
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118400/