FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal
Puma is an essential mediator of p53-dependent and -independent apoptosis in vivo. In response to genotoxic stress, Puma is induced in a p53-dependent manner. However, the transcription factor driving Puma up-regulation in response to p53-independent apoptotic stimuli has yet to be identified. Here,...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118330/ |