Nepmucin, a novel HEV sialomucin, mediates L-selectin–dependent lymphocyte rolling and promotes lymphocyte adhesion under flow

Nepmucin, a novel HEV sialomucin, mediates L-selectin–dependent lymphocyte rolling and promotes lymphocyte adhesion under flow

Lymphocyte trafficking to lymph nodes (LNs) is initiated by the interaction between lymphocyte L-selectin and certain sialomucins, collectively termed peripheral node addressin (PNAd), carrying specific carbohydrates expressed by LN high endothelial venules (HEVs). Here, we identified a novel HEV-as...

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Bibliographic Details
Main Authors: Umemoto, Eiji, Tanaka, Toshiyuki, Kanda, Hidenobu, Jin, Soojung, Tohya, Kazuo, Otani, Kazuhiro, Matsutani, Takahiro, Matsumoto, Masanori, Ebisuno, Yukihiko, Jang, Myoung Ho, Fukuda, Minoru, Hirata, Takako, Miyasaka, Masayuki
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118321/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118321/

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