Systemic antithrombotic effects of ADAMTS13
The metalloprotease ADAMTS13 (a disintegrin-like and metalloprotease with thrombospondin type I repeats 13) cleaves highly adhesive large von Willebrand factor (VWF) multimers after their release from the endothelium. ADAMTS13 deficiency is linked to a life-threatening disorder, thrombotic thrombocy...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118248/ |