Systemic antithrombotic effects of ADAMTS13

The metalloprotease ADAMTS13 (a disintegrin-like and metalloprotease with thrombospondin type I repeats 13) cleaves highly adhesive large von Willebrand factor (VWF) multimers after their release from the endothelium. ADAMTS13 deficiency is linked to a life-threatening disorder, thrombotic thrombocy...

Full description

Bibliographic Details
Main Authors: Chauhan, Anil K., Motto, David G., Lamb, Colin B., Bergmeier, Wolfgang, Dockal, Michael, Plaimauer, Barbara, Scheiflinger, Friedrich, Ginsburg, David, Wagner, Denisa D.
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118248/