Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor γ activity

Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor γ activity

Colitis involves immune cell–mediated tissue injuries, but the contribution of epithelial cells remains largely unclear. Vanin-1 is an epithelial ectoenzyme with a pantetheinase activity that provides cysteamine/cystamine to tissue. Using the 2,4,6-trinitrobenzene sulfonic acid (TNBS)-colitis model...

Full description

Bibliographic Details
Main Authors: Berruyer, Carole, Pouyet, Laurent, Millet, Virginie, Martin, Florent M., LeGoffic, Aude, Canonici, Alexandra, Garcia, Stéphane, Bagnis, Claude, Naquet, Philippe, Galland, Franck
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118186/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118186/

Similar Items