Induction of a virus-specific effector–memory CD4+ T cell response by attenuated SIV infection

We investigated simian immunodeficiency virus (SIV)-specific CD4+ T cell responses in rhesus macaques chronically infected with attenuated or pathogenic SIV strains. Analysis of SIVΔnef-infected animals revealed a relatively high frequency of SIV-specific CD4+ T cells representing 4–10% of all CD4+...

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Bibliographic Details
Main Authors: Gauduin, Marie-Claire, Yu, Yi, Barabasz, Amy, Carville, Angela, Piatak, Mike, Lifson, Jeffrey D., Desrosiers, Ronald C., Johnson, R. Paul
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118155/