Giving blood: a new role for CD40 in tumorigenesis
CD40 was initially identified as a receptor expressed by B cells that is crucial for inducing an effective adaptive immune response. CD40 was subsequently shown to be expressed by endothelial cells and to promote angiogenesis. New data now show that in tumor-prone transgenic mice, CD40-mediated neov...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118122/ |