Giving blood: a new role for CD40 in tumorigenesis

CD40 was initially identified as a receptor expressed by B cells that is crucial for inducing an effective adaptive immune response. CD40 was subsequently shown to be expressed by endothelial cells and to promote angiogenesis. New data now show that in tumor-prone transgenic mice, CD40-mediated neov...

Full description

Bibliographic Details
Main Authors: Bergmann, Stephan, Pandolfi, Pier Paolo
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118122/