Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

Th17 cells are a distinct lineage of effector CD4+ T cells characterized by their production of interleukin (IL)-17. We demonstrate that Th17 cells also expressed IL-22, an IL-10 family member, at substantially higher amounts than T helper (Th)1 or Th2 cells. Similar to IL-17A, IL-22 expression was...

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Bibliographic Details
Main Authors: Liang, Spencer C., Tan, Xiang-Yang, Luxenberg, Deborah P., Karim, Riyez, Dunussi-Joannopoulos, Kyriaki, Collins, Mary, Fouser, Lynette A.
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118116/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118116/

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