Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro- beta-NGF in vivo

Extracts from BSC-40 cells infected with vaccinia recombinants expressing either the yeast KEX2 prohormone endoprotease or a human structural homologue (fur gene product) contained an elevated level of a membrane-associated endoproteolytic activity that could cleave at pairs of basic amino acids (-L...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1990
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2116363/