The human alpha 2-macroglobulin receptor: identification of a 420-kD cell surface glycoprotein specific for the activated conformation of alpha 2-macroglobulin

Ligand affinity chromatography was used to purify a cell surface alpha 2-macroglobulin (alpha 2M) receptor. Detergent extracts of human placenta were applied to an affinity matrix consisting of alpha 2M, previously reacted with methylamine, coupled to Sepharose. Elution with EDTA specifically releas...

Full description

Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1990
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2116111/