Norepinephrine down-regulates the activity of protein S on endothelial cells
The adrenergic agonist norepinephrine is shown to stimulate endothelium to induce protein S release and degradation, leading to diminished anti- coagulant activity and to down-regulation of protein S cell surface- binding sites. Norepinephrine-induced release of intracellular protein S was blocked b...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1988
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2115154/ |