Correction of abnormal matrix formed by cmd/cmd chondrocytes in culture by exogenously added cartilage proteoglycan
The cartilage matrix deficiency (cmd/cmd) mouse fails to synthesize the core protein of cartilage-characteristic proteoglycan (cartilage PG). Chondrocytes from the cmd/cmd cartilage cultured in vitro produced nodules with greatly reduced extracellular matrix. Immunofluorescence staining revealed tha...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1986
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114350/ |