DNA amplification in multidrug, cross-resistant Chinese hamster ovary cells: molecular characterization and cytogenetic localization of the amplified DNA
Vincristine-resistant (VCR) Chinese hamster ovary (CHO) cells have been established by stepwise selection in increasing concentrations of vincristine. These cells exhibit multidrug cross-resistance to a number of drugs that have no structural or functional similarities. Cytogenetic analyses of resis...
| Format: | Online |
|---|---|
| Language: | English |
| Published: |
The Rockefeller University Press
1986
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114345/ |