Autoregulation of tubulin synthesis in hepatocytes and fibroblasts

Microtubule polymer levels in mouse 3T6 fibroblasts and primary cultures of rat hepatocytes can be manipulated by treatment of cells with long term, low doses of colcemid. Such treatment produces a rather uniform population of cells with microtubules of reduced lengths. Using this system, we demonst...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1985
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113958/