Transforming growth factor-beta modulates the high-affinity receptors for epidermal growth factor and transforming growth factor-alpha

The epidermal growth factor (EGF) receptor mediates the induction of a transformed phenotype in normal rat kidney (NRK) cells by transforming growth factors (TGFs). The ability of EGF and its analogue TGF-alpha to induce the transformed phenotype in NRK cells is greatly potentiated by TGF-beta, a po...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1985
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113854/