Internalization and degradation of macrophage Fc receptors bound to polyvalent immune complexes

We have studied the Fc receptor-mediated pinocytosis of immunoglobulin G (IgG)-containing immune complexes by mouse macrophages. IgG complexes were formed from affinity-purified rabbit dinitrophenyl IgG and dinitrophenyl modified BSA at molar ratios of 2.5-10:1. Both the specificity of binding and t...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1984
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113248/