Excitation, adaption, and deadaptation of the cAMP-mediated cGMP Response in dictyostelium discoideum
Extracellular cAMP induces chemotaxis and cell aggregation in dictyostelium discoideum cells. cAMP added to a cell suspension is rapidly hydrolyzed (half-life of 10 s) and induces a rapid increase of intracellular cGMP levels, which reach a peak at 10 s and recover prestimulated levels at about 30 s...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
1983
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2112281/ |