Transformation of isolated rat hepatocytes with simian virus 40

Rat hepatocytes were transformed by simian virus 40 (SV40). Hepatocytes from two different strains of rats and a temperature-sensitive mutant (SV40tsA 1609), as well as wild-type virus were used. In all cases, transformed cells arose from approximately 50% of the cultures containing hepatocytes on c...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1980
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2111450/