Recombinant Interleukin-24 Lacks Apoptosis-Inducing Properties in Melanoma Cells

IL-24, also known as melanoma differentiation antigen 7 (mda-7), is a member of the IL-10 family of cytokines and is mainly produced by Th2 cells as well as by activated monocytes. Binding of IL-24 to either of its two possible heterodimeric receptors IL-20R1/IL-20R2 and IL-22R/IL-20R2 activates STA...

Full description

Bibliographic Details
Main Authors: Kreis, Stephanie, Philippidou, Demetra, Margue, Christiane, Rolvering, Catherine, Haan, Claude, Dumoutier, Laure, Renauld, Jean-Christophe, Behrmann, Iris
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110900/