ZINC REQUIREMENT FOR DNA REPLICATION IN STIMULATED HUMAN LYMPHOCYTES

The requirement for Zn++ in DNA replication by phytohemagglutinin-stimulated human lymphocytes was studied. When 6 µM o-phenanthroline, a chelator with a high affinity for Zn++, is added to cultures of stimulated lymphocytes a nearly complete inhibition of thymidine incorporation results within a f...

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Bibliographic Details
Main Authors: Williams, Richard O., Loeb, Lawrence A.
Format: Online
Language:English
Published: The Rockefeller University Press 1973
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109070/