SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis

SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis

From 61 to 92% of the total sialic acid of a variety of human lymphoid cell lines maintained in tissue culture is present on the cell surface as measured by its susceptibility to cleavage by Clostridium perfringens neuraminidase. These cells contain from 1.22 x 108 to 6.99 x 108 molecules of surfac...

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Main Authors: Rosenberg, Steven A., Einstein, Albert B.
Format: Online
Language:English
Published: The Rockefeller University Press 1972
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108726/
id pubmed-2108726
recordtype oai_dc
spelling pubmed-21087262008-05-01 SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis Rosenberg, Steven A. Einstein, Albert B. Article From 61 to 92% of the total sialic acid of a variety of human lymphoid cell lines maintained in tissue culture is present on the cell surface as measured by its susceptibility to cleavage by Clostridium perfringens neuraminidase. These cells contain from 1.22 x 108 to 6.99 x 108 molecules of surface sialic acid per cell. In synchronized cultures synthesis of surface sialic acid occurs only during a limited time in the late G2 phase of the cell cycle. The amount and density of surface sialic acid vary considerably throughout the cell cycle. The Rockefeller University Press 1972-05-01 /pmc/articles/PMC2108726/ /pubmed/4502785 Text en Copyright © 1972 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Rosenberg, Steven A.
Einstein, Albert B.
spellingShingle Rosenberg, Steven A.
Einstein, Albert B.
SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
author_facet Rosenberg, Steven A.
Einstein, Albert B.
author_sort Rosenberg, Steven A.
title SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
title_short SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
title_full SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
title_fullStr SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
title_full_unstemmed SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
title_sort sialic acids on the plasma membrane of cultured human lymphoid cells : chemical aspects and biosynthesis
description From 61 to 92% of the total sialic acid of a variety of human lymphoid cell lines maintained in tissue culture is present on the cell surface as measured by its susceptibility to cleavage by Clostridium perfringens neuraminidase. These cells contain from 1.22 x 108 to 6.99 x 108 molecules of surface sialic acid per cell. In synchronized cultures synthesis of surface sialic acid occurs only during a limited time in the late G2 phase of the cell cycle. The amount and density of surface sialic acid vary considerably throughout the cell cycle.
publisher The Rockefeller University Press
publishDate 1972
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108726/
_version_ 1611410179313631232

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