DEGRADATION OF RIBONUCLEIC ACID IN MOUSE FIBROBLASTS TREATED WITH ACTINOMYCIN

The cellular RNA content of mouse fibroblasts incubated with actinomycin decreases at a rate of about 1 to 1.5 per cent per hour, while DNA and protein content remain unchanged. This degradation affects nuclear and cytoplasmic RNA, ribosomal and soluble RNA. The breakdown products appear quantitati...

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Bibliographic Details
Main Authors: Wiesner, R., Acs, G., Reich, E., Shafiq, A.
Format: Online
Language:English
Published: The Rockefeller University Press 1965
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106805/