Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells
Dendritic cells efficiently internalize exogenous protein antigens by fluid-phase uptake and receptor-mediated endocytosis. Such antigens contribute to cross-presentation by being translocated into the cytosol for proteasomal degradation, which liberates immunogenic peptides that can bind to major h...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Nature Publishing Group
2008
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2104710/ |