Conserved lysine 79 is important for activity of ecto-nucleoside triphosphate diphosphohydrolase 3 (NTPDase3)

Cell membrane-bound ecto-nucleoside triphosphate diphosphohydrolases (NTPDases) are homooligomeric, with native quaternary structure required for maximal enzyme activity. In this study, we mutated lysine 79 in human ecto-nucleoside triphosphate diphosphohydrolase 3 (NTPDase3). The residue correspond...

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Bibliographic Details
Main Authors: Basu, Saswata, Murphy-Piedmonte, Deirdre M., Kirley, Terence L.
Format: Online
Language:English
Published: Springer Netherlands 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096571/