The human checkpoint sensor Rad9–Rad1–Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase

Human (h) DNA repair enzyme thymine DNA glycosylase (hTDG) is a key DNA glycosylase in the base excision repair (BER) pathway that repairs deaminated cytosines and 5-methyl-cytosines. The cell cycle checkpoint protein Rad9–Rad1–Hus1 (the 9-1-1 complex) is the surveillance machinery involved in the p...

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Bibliographic Details
Main Authors: Guan, Xin, Madabushi, Amrita, Chang, Dau-Yin, Fitzgerald, Megan E., Shi, Gouli, Drohat, Alexander C., Lu, A-Lien
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094074/