A Network Analysis of the Human T-Cell Activation Gene Network Identifies Jagged1 as a Therapeutic Target for Autoimmune Diseases

Understanding complex diseases will benefit the recognition of the properties of the gene networks that control biological functions. Here, we set out to model the gene network that controls T-cell activation in humans, which is critical for the development of autoimmune diseases such as Multiple Sc...

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Bibliographic Details
Main Authors: Palacios, Ricardo, Goni, Joaquin, Martinez-Forero, Ivan, Iranzo, Jaime, Sepulcre, Jorge, Melero, Ignacio, Villoslada, Pablo
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077806/