Serotonin 2C Receptor Agonists Improve Type 2 Diabetes via Melanocortin-4 Receptor Signaling Pathways

The burden of type 2 diabetes and its associated premature morbidity and mortality is rapidly growing, and the need for novel efficacious treatments is pressing. We report here that serotonin 2C receptor (5-HT2CR) agonists, typically investigated for their anorectic properties, significantly improve...

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Bibliographic Details
Main Authors: Zhou, Ligang, Sutton, Gregory M., Rochford, Justin J., Semple, Robert K., Lam, Daniel D., Oksanen, Laura J., Thornton-Jones, Zoe D., Clifton, Peter G., Yueh, Chen-Yu, Evans, Mark L., McCrimmon, Rory J., Elmquist, Joel K., Butler, Andrew A., Heisler, Lora K.
Format: Online
Language:English
Published: Cell Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075535/