The different effector function capabilities of the seven equine IgG subclasses have implications for vaccine strategies
Recombinant versions of the seven equine IgG subclasses were expressed in CHO cells. All assembled into intact immunoglobulins stabilised by disulphide bridges, although, reminiscent of human IgG4, a small proportion of equine IgG4 and IgG7 were held together by non-covalent bonds alone. All seven I...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Pergamon Press
2008
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075531/ |