Allelic loss at chromosome 13q12-q13 is associated with poor prognosis in familial and sporadic breast cancer.
Loss of heterozygosity (LOH) was analysed in 84 primary tumours from sporadic, familial and hereditary breast cancer using five microsatellite markers spanning the chromosomal region 13q12-q13 which harbours the BRCA2 breast cancer susceptibility gene, and using one other marker located within the R...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Nature Publishing Group
1996
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074869/ |