Enhancement of anti-tumour immunity in syngeneic mice after MHC class II gene transfection.

The relationship between tumorigenicity and expression of MHC class II molecules in a class II-negative murine leukaemia cell line (LBC) was studied. Analysis of structural DNA sequences encoding MHC class II proteins was performed by Southern blot with DNA isolated from both the original LB tumour...

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Bibliographic Details
Main Authors: Mongini, C., Sánchez Lockhart, M., Waldner, C. I., Alvarez, E. M., Gravisaco, M. J., Roig, M. I., Hajos, S. E.
Format: Online
Language:English
Published: Nature Publishing Group 1996
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074574/