Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres
Organ homeostasis and organismal survival are related to the ability of stem cells to sustain tissue regeneration. As a consequence of accelerated telomerase shortening, telomerase-deficient mice show defective tissue regeneration and premature death. This suggests a direct impact of telomere length...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064764/ |