Msk is required for nuclear import of TGF-β/BMP-activated Smads

Nuclear translocation of Smad proteins is a critical step in signal transduction of transforming growth factor β (TGF-β) and bone morphogenetic proteins (BMPs). Using nuclear accumulation of the Drosophila Smad Mothers against Decapentaplegic (Mad) as the readout, we carried out a whole-genome RNAi...

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Bibliographic Details
Main Authors: Xu, Lan, Yao, Xiaohao, Chen, Xiaochu, Lu, Peiyuan, Zhang, Biliang, Ip, Y. Tony
Format: Online
Language:English
Published: The Rockefeller University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064622/