Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation
During cotranslational protein targeting, two guanosine triphosphatase (GTPase) in the signal recognition particle (SRP) and its receptor (SR) form a unique complex in which hydrolyses of both guanosine triphosphates (GTP) are activated in a shared active site. It was thought that GTP hydrolysis dri...
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Rockefeller University Press|1
2007
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064468/ |