p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

Clearance of fibrin through proteolytic degradation is a critical step of matrix remodeling that contributes to tissue repair in a variety of pathological conditions, such as stroke, atherosclerosis, and pulmonary disease. However, the molecular mechanisms that regulate fibrin deposition are not kno...

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Bibliographic Details
Main Authors: Sachs, Benjamin D., Baillie, George S., McCall, Julianne R., Passino, Melissa A., Schachtrup, Christian, Wallace, Derek A., Dunlop, Allan J., MacKenzie, Kirsty F., Klussmann, Enno, Lynch, Martin J., Sikorski, Shoana L., Nuriel, Tal, Tsigelny, Igor, Zhang, Jin, Houslay, Miles D., Chao, Moses V., Akassoglou, Katerina
Format: Online
Language:English
Published: The Rockefeller University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064370/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064370/

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