Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane
Stromal interacting molecule 1 (STIM1), reported to be an endoplasmic reticulum (ER) Ca2+ sensor controlling store-operated Ca2+ entry, redistributes from a diffuse ER localization into puncta at the cell periphery after store depletion. STIM1 redistribution is proposed to be necessary for Ca2+ rele...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
2006
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064335/ |