Functional implications of calcium permeability of the channel formed by pannexin 1

Although human pannexins (PanX) are homologous to gap junction molecules, their physiological function in vertebrates remains poorly understood. Our results demonstrate that overexpression of PanX1 results in the formation of Ca2+-permeable gap junction channels between adjacent cells, thus, allowin...

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Bibliographic Details
Main Authors: Vanden Abeele, Fabien, Bidaux, Gabriel, Gordienko, Dmitri, Beck, Benjamin, Panchin, Yuri V., Baranova, Ancha V., Ivanov, Dmitry V., Skryma, Roman, Prevarskaya, Natalia
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064259/