Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases

Development, angiogenesis, wound healing, and metastasis all involve the movement of cells in response to changes in the extracellular environment. To determine whether caveolin-1 plays a role in cell migration, we have used fibroblasts from knockout mice. Caveolin-1–deficient cells lose normal cell...

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Bibliographic Details
Main Authors: Grande-García, Araceli, Echarri, Asier, de Rooij, Johan, Alderson, Nazilla B., Waterman-Storer, Clare M., Valdivielso, José M., del Pozo, Miguel A.
Format: Online
Language:English
Published: The Rockefeller University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064213/