Prostaglandin E2 potentiation of P2X3 receptor mediated currents in dorsal root ganglion neurons

Prostaglandin E2 (PGE2) is a well-known inflammatory mediator that enhances the excitability of DRG neurons. Homomeric P2X3 and heteromeric P2X2/3 receptors are abundantly expressed in dorsal root ganglia (DRG) neurons and participate in the transmission of nociceptive signals. The interaction betwe...

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Bibliographic Details
Main Authors: Wang, Congying, Li, Guang-Wen, Huang, Li-Yen Mae
Format: Online
Language:English
Published: BioMed Central 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063498/