Prostaglandin E2 potentiation of P2X3 receptor mediated currents in dorsal root ganglion neurons
Prostaglandin E2 (PGE2) is a well-known inflammatory mediator that enhances the excitability of DRG neurons. Homomeric P2X3 and heteromeric P2X2/3 receptors are abundantly expressed in dorsal root ganglia (DRG) neurons and participate in the transmission of nociceptive signals. The interaction betwe...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063498/ |