Antiproliferative effect of methyl-beta-cyclodextrin in vitro and in human tumour xenografted athymic nude mice.

The anti-tumour activity of methyl-beta-cyclodextrin (MEBCD), a cyclic oligosaccharide known for its interaction with the plasma membrane, was investigated in vitro and in vivo and compared with that of doxorubicin (DOX) in the human tumour models MCF7 breast carcinoma and A2780 ovarian carcinoma. I...

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Bibliographic Details
Main Authors: Grosse, P. Y., Bressolle, F., Pinguet, F.
Format: Online
Language:English
Published: Nature Publishing Group|1 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2062988/