Loss of heterozygosity occurs at the D11S29 locus on chromosome 11q23 in invasive cervical carcinoma.
Allelotypic detection of loss of heterozygosity (LOH) has been used to identify putative tumour-suppressor genes. Loci on human chromosome 11q23 are frequently altered in malignant disease, and LOH has been reported at an anonymous D11S29 locus at 11q23 in a proportion of breast and ovarian cancers...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1995
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033723/ |