P-glycoprotein and glutathione S-transferase pi in childhood acute lymphoblastic leukaemia.

Blast cells obtained from 104 children with untreated acute lymphoblastic leukaemia were analysed for the expression of P-glycoprotein (P-170) and glutathione S-transfer pi (GST-pi) using immunohistochemistry. Expression of P-170 was detected in 36 of 104 patients (35%) and increased GST-pi was seen...

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Bibliographic Details
Main Authors: Sauerbrey, A., Zintl, F., Volm, M.
Format: Online
Language:English
Published: 1994
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033687/