Modification of the photodynamic action of delta-aminolaevulinic acid (ALA) on rat pancreatoma cells by mitochondrial benzodiazepine receptor ligands.

We have shown that addition of exogenous delta-aminolaevulinic acid (ALA) to rat pancreatoma AR4-2J cells in culture leads to the increased production of porphobilinogen (PBG) and the accumulation of photoactive protoporphyrin IX (PPix) in these cells. Exposure to light (lambda > 400 nm) at an in...

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Bibliographic Details
Main Authors: Ratcliffe, S. L., Matthews, E. K.
Format: Online
Language:English
Published: 1995
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033603/