Combination therapy with cisplatin and nifedipine induces apoptosis in cisplatin-sensitive and cisplatin-resistant human glioblastoma cells.

We attempted to determine whether calcium channel blockers (CCBs) enhance the anti-tumour activity of cis-diamminedichloroplatinum (cisplatin) against both cisplatin-sensitive human glioblastoma U87 MG cells and cisplatin-resistant U87-MG-CR cells, the latter of which we developed for resistance to...

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Bibliographic Details
Main Authors: Kondo, S., Yin, D., Morimura, T., Kubo, H., Nakatsu, S., Takeuchi, J.
Format: Online
Language:English
Published: 1995
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033593/