Effects of 4-hydroxytamoxifen and a novel pure antioestrogen (ICI 182780) on the clonogenic growth of human breast cancer cells in vitro.

We have investigated the effects on breast cancer cell growth of 4-hydroxytamoxifen (4OHT), a conventional antioestrogen with agonist activity, and 7 alpha-[9-(4,4,5,5,5-pentafluoropentylsulphinyl)nonyl]oestra- 1,3,5,(10)- triene-3,17 beta-diol (ICI 182780), a novel, pure antioestrogen, using establ...

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Bibliographic Details
Main Authors: DeFriend, D. J., Anderson, E., Bell, J., Wilks, D. P., West, C. M., Mansel, R. E., Howell, A.
Format: Online
Language:English
Published: 1994
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033516/